Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Antimorphic

Synonym(s): negative dominant

Antimorphic is a dominant loss-of-function mutation. It is common with homo-dimers and some -multimers when the mutated protein negatively affects the function of the protein complex, so also the normal protein becomes ineffective and cannot compensate the loss of function.

Related terms:

hypomorphic amorphic hypermorphic neomorphic
Copyright © 2005-2020 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD
Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944
Sitemap | Webmail | Disclaimer | Privacy Issues