Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Hereditary renal tumors

The heterogeneous group of kidney tumors is characterized by varied degree of malignancy, origination from different tissues even outside the kidneys, and diverse genetic background.

Epidemiology

Renal cancer is the 7th leading cancer among men an the 12th among women. 2.6% of renal cancers are hereditary disorders.

Systematic

Hereditary kidney diseases
Congenital abnormalities of the kidney and urinary tract
Cystic kidney disease
Disorders of tubular solute transport
Hereditary glomerular disease
Hereditary metabolic kidney disease
Hereditary renal tumors
Hereditary leiomyomatosis and renal cell cancer
COL4A6
FH
Hereditary papillary renal cell carcinoma
Hereditary papillary renal cell carcinoma 1
MET
PRCC
Nonpapillary renal cell carcinoma
DIRC2
FLCN
HNF1A
HNF1B
OGG1
RNF139
VHL
Wilms tumor
Aniridia-Wilms-tumor syndrome
PAX6
WT1
Denys-Drash syndrome
WT1
Somatic nephroblastoma
GPC3
WT1
WAGR syndrome
PAX6
WT1
von Hippel-Lindau syndrome
VHL
Interstitial kidney disease
Kidney disease appearing as endocrinological disorders
Thrombotic microangiopathies
Urolithiasis

References:

1.

Cohen HT et al. (2005) Renal-cell carcinoma.

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2.

Orphanet article

Orphanet ID 217071 [^]
Update: April 29, 2019