Central diabetes insipidus
Central diabetes insipidus results from inappropriate production of the antidiuretic hormone arginine vasopressin and can ameliorated by hormone supplementation.
There are several aquired conditions which result in syndrome of inappropriate antidiuretic hormone
Polyuria can be remarkably reduced with AVP administration.
|Hereditary diabetes insipidus|
|Central diabetes insipidus|
|Nephrogenic diabetes insipidus|
Bahnsen U et al. (1992) A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus.[^]
Ito M et al. (1991) A single base substitution in the coding region for neurophysin II associated with familial central diabetes insipidus.[^]
Ito M et al. (1993) Possible involvement of inefficient cleavage of preprovasopressin by signal peptidase as a cause for familial central diabetes insipidus.[^]
Grant FD et al. (1998) Two novel mutations of the vasopressin gene associated with familial diabetes insipidus and identification of an asymptomatic carrier infant.[^]