Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Alloimmune thrombocytopenia

Alloimmune thrombocytopenia is a blleding disorder of the newborn that results from maternal allo-antibodies against fetal platelets. The reason for these allo-antibodies is the fetus bears a platelet antigen inherited from its father for which the mother did not develop immuno-tolerance.

Systematic

Inheritable platelet disorders
Alloimmune thrombocytopenia
ITGA2B
ITGB3
Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia
Bernard-Soulier syndrome
Bleeding disorder platelet-type 9
Glycoprotein 1a deficiency
IVIC syndrome
MYH9 related disorders
Mediterranean macrothrombocytopenia
Thrombasthenia of Glanzmann and Naegeli
Thrombocythemia 3
Wiskott–Aldrich syndrome

References:

1.

Kher A et al. (2007) The management of thrombosis in pregnancy: role of low-molecular-weight heparin.

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2.

OMIM.ORG article

Omim 173470 [^]
Update: April 29, 2019