Hyperinsulinemic hypoglycemia 5
Congenital hyperinsulinism, nesidioblastosis is the most common cause of persistent hypoglycemia in infancy which is caused by increased insulin secretion despite of low blood glycose levels. The most important complication is cerebral damage as a result of prolonged hypoglycemia. Type 5 of the disease is caused by INSR mutations.
Højlund K et al. (2004) A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene.[^]
OMIM.ORG articleOmim 609968 [^]