Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Hyperinsulinemic hypoglycemia 5

Congenital hyperinsulinism, nesidioblastosis is the most common cause of persistent hypoglycemia in infancy which is caused by increased insulin secretion despite of low blood glycose levels. The most important complication is cerebral damage as a result of prolonged hypoglycemia. Type 5 of the disease is caused by INSR mutations.

Systematic

Hyperinsulinemic hypoglycemia
HNF1A
HNF4A
Hyperinsulinemic hypoglycemia 1
Hyperinsulinemic hypoglycemia 2
Hyperinsulinemic hypoglycemia 3
Hyperinsulinemic hypoglycemia 4
Hyperinsulinemic hypoglycemia 5
INSR
Hyperinsulinemic hypoglycemia 6
Hyperinsulinemic hypoglycemia 7
Polycystic kidney disease with hyperinsulinemic hypoglycemia

References:

1.

Højlund K et al. (2004) A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene.

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2.

OMIM.ORG article

Omim 609968 [^]
Update: April 29, 2019