Disturbances of vitamin K metabolism
if vitamin K metabolism is disturbed a bleeding disorder similar to wafarin medication ensues. A combined factor II, VII, IX, and X deficiency is observed.
Rost S et al. (2004) Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.[^]
Garcia AA et al. (2008) VKORC1 and the vitamin K cycle.[^]