Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Short QT syndrome

The short QT syndrome is a hereditary arrythmia in which the QT interval measured by ECG is shorter than usual. Short QT syndrome is characterized by life threatening recurrent ventricular arrhythmias and is caused by disturbances of transmembrane transport.

Systematic

Hereditary arrhythmia
Long QT syndrome
Short QT syndrome
Short QT syndrome 1
KCNH2
Short QT syndrome 2
KCNQ1
Short QT syndrome 3
KCNJ2

References:

1.

Hong K et. al. (2005) Short QT syndrome and atrial fibrillation caused by mutation in KCNH2.

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2.

Priori SG et. al. (2005) A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene.

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3.

Bellocq C et. al. (2004) Mutation in the KCNQ1 gene leading to the short QT-interval syndrome.

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4.

Gouas L et. al. (2005) Association of KCNQ1, KCNE1, KCNH2 and SCN5A polymorphisms with QTc interval length in a healthy population.

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5.

Schimpf R et. al. (2005) Short QT syndrome.

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6.

Moreno C et. al. (2015) A new KCNQ1 mutation at the S5 segment that impairs its association with KCNE1 is responsible for short QT syndrome.

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Update: Sept. 26, 2018