Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Dilated cardiomyopathy 1A

Dilated cardiomyopathy 1A is an autosomal dominant disorder caused by mutations of the LMNA gene. The disease is characterized by progressive cardiac failure , conduction disturbances and is a frequent cause of transplantation.

Systematic

Hereditary cardiomyopathy
Dilated cardiomyopathy 1A
LMNA
Malouf syndrome

References:

1.

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2.

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3.

Taylor MR et al. (2003) Natural history of dilated cardiomyopathy due to lamin A/C gene mutations.

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Charniot JC et al. (2003) Functional consequences of an LMNA mutation associated with a new cardiac and non-cardiac phenotype.

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41.

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OMIM.ORG article

Omim 115200 [^]
Update: April 29, 2019