Open angle glaucoma 1M
Open angle glaucoma 1M is a disease that manifests in early adulthood. Although hereditary its genetic cause is not completely discovered. Genetic localization is the 5q22.1-q32 chromosomal region.
Wang DY et al. (2004) Absence of myocilin and optineurin mutations in a large Philippine family with juvenile onset primary open angle glaucoma.[^]
Pang CP et al. (2006) A genome-wide scan maps a novel juvenile-onset primary open angle glaucoma locus to chromosome 5q.[^]
Fan BJ et al. (2007) Fine mapping of new glaucoma locus GLC1M and exclusion of neuregulin 2 as the causative gene.[^]
OMIM.ORG articleOmim 610535 [^]