Open angle glaucoma 1P
Open angle glaucoma 1P is a disease that manifests in early adulthood. Although hereditary its genetic cause is not completely discovered. Genetic localization is the 12q14 chromosomal region.
Bennett SR et. al. (1989) An autosomal dominant form of low-tension glaucoma.[^]
None (1961) Pseudoglaucoma of autosomal, dominant inheritance. A report on three families.[^]
Fingert JH et. al. (2011) Copy number variations on chromosome 12q14 in patients with normal tension glaucoma.[^]
Kawase K et. al. (2012) Confirmation of TBK1 duplication in normal tension glaucoma.[^]
Fingert JH et. al. (2014) TBK1 and flanking genes in human retina.[^]
Awadalla MS et. al. (2015) Copy number variations of TBK1 in Australian patients with primary open-angle glaucoma.[^]