Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Fasting plasma glucose trait loci

Genetic alterations at some loci may influence fasting blood glucose, so these loci are involved in glucose metabolism and may influence the course of diabetes.

Systematic

Disturbances of glucose metabolism
Diabetes mellitus
Disturbed regulators of lipid and carbohydrate metabolism
Fasting plasma glucose trait loci
G6PC2
GCKR
Hyperinsulinemic hypoglycemia
Hypoinsulinemic hypoglycemia

References:

1.

Dupuis J et al. (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

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2.

Bouatia-Naji N et al. (2008) A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.

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3.

Chen WM et al. (2008) Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.

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4.

Prokopenko I et al. (2009) Variants in MTNR1B influence fasting glucose levels.

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5.

OMIM.ORG article

Omim 612108 [^]
Update: April 29, 2019