Inflammatory bowel disease 13
The disposition to develop inflammatory bowel disease is hereditary. For type 13, the gene ABCB1 is responsible.
Panwala CM et. al. (1998) A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis.[^]
Brant SR et. al. (2003) MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.[^]
Ho GT et. al. (2006) ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach.[^]
Satsangi J et. al. (1996) Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12.[^]
Cho JH et. al. (1998) Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.[^]
Kim RB et. al. (2001) Identification of functionally variant MDR1 alleles among European Americans and African Americans.[^]