Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Plasma triglyceride level quantitative trait locus

The disposition to develop hight triglyceride levels is hereditary. Among others, the gene ANGPTL4 is responsible.

Systematic

Hypertriglyceridemia
APOA5
APOE
Combined lipase deficiency
GPIHBP1
LIPC
LIPE
LPL
Plasma triglyceride level quantitative trait locus
ANGPTL4
Transient infantile hypertriglyceridemia

References:

1.

Romeo S et. al. (2009) Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.

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2.

Dewey FE et. al. (2016) Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

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3.

et. al. (2016) Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

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Update: Sept. 26, 2018