Obesity, adrenal insufficiency, and red hair due to POMC deficiency
Mutations in the POMC gene can lead to a deficiency accompanied by adrenal insufficiency, obesity, and redhairedness.
Krude H et al. (1998) Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans.[^]
Yaswen L et al. (1999) Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin.[^]
Krude H et al. (2003) Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.[^]
OMIM.ORG articleOmim 609734 [^]