Watson syndrome is an autosomal dominant disorder caused by mutations of the NF1 gene. It is characteized by cafe-au-lait spots are associated with pulmonic stensis.
|Café au lait spots|
In Watson syndrome cafe-au-lait spots are associated with pulmonic stensis.
|Familial spinal neurofibromatosis|
|Noonan syndrome 6|
Upadhyaya M et. al. (1992) Analysis of mutations at the neurofibromatosis 1 (NF1) locus.[^]
Allanson JE et. al. (1991) Watson syndrome: is it a subtype of type 1 neurofibromatosis?[^]
Tassabehji M et. al. (1993) Tandem duplication within a neurofibromatosis type 1 (NF1) gene exon in a family with features of Watson syndrome and Noonan syndrome.[^]
Sharland M et. al. (1992) Absence of linkage of Noonan syndrome to the neurofibromatosis type 1 locus.[^]
None (1967) Pulmonary stenosis, café-au-lait spots, and dull intelligence.[^]