Metabolic bone disease
This group includes all kinds of familial disposition to skeletal problems, including fragility fractures, osteoporosis, osteopathy etc.
To this group belong the whole spectrum from monogenic disorders, which are rare, to polygenic conditions, which are frequent. Click on the disease to study that in more detail.
The clinical picture is dominated by frequent fractures, bone pain, and sometimes extraskeletal calcifications.
The diagnosis is made by clinical examination, family history, bone density measurements and x-ray. The varied laboratory findings are in detail discussed when clicking each diseases.
Not only in the bone itself but also in other organs, such as kidney, liver, gut, and parathyroid gland might be the cause of the disease.