Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Non-medullary thyroid cancer 4

Hereditary non-medullary thyroid cancer 4 is an autosomal dominant disorder caused by mutations of the FOXE1 gene.

Systematic

Non-medullary thyroid cancer
Familial follicular thyroid carcinoma
Follicular thyroid carcinoma
Hyperfunctioning thyroid adenoma
Non-medullary thyroid cancer 2
Non-medullary thyroid cancer 3
Non-medullary thyroid cancer 4
Non-medullary thyroid cancer 4
FOXE1
Non-medullary thyroid cancer 5
Thyroid carcinoma with thyrotoxicosis

References:

1.

Pereira JS et al. (2015) Identification of a novel germline FOXE1 variant in patients with familial non-medullary thyroid carcinoma (FNMTC).

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2.

Denny JC et al. (2011) Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.

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3.

Gudmundsson J et al. (2009) Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.

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4.

Takahashi M et al. (2010) The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.

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5.

OMIM.ORG article

Omim 616534 [^]
Update: April 29, 2019