Hereditary non-medullary thyroid cancer 2 is an autosomal dominant disorder caused by mutations of the SRGAP1 and MINPP1 genes. Also in tumors somatic mutation in the genes NRAS and HRAS are found.
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He H et al. (2013) SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility. |
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Vriens MR et al. (2009) Clinical features and genetic predisposition to hereditary nonmedullary thyroid cancer. |
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Bonora E et al. (2010) Genetic Predisposition to Familial Nonmedullary Thyroid Cancer: An Update of Molecular Findings and State-of-the-Art Studies. |
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OMIM.ORG article Omim 188470 |