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Non-medullary thyroid cancer 2

Hereditary non-medullary thyroid cancer 2 is an autosomal dominant disorder caused by mutations of the SRGAP1 and MINPP1 genes. Also in tumors somatic mutation in the genes NRAS and HRAS are found.

Systematic

Non-medullary thyroid cancer
Familial follicular thyroid carcinoma
Follicular thyroid carcinoma
Hyperfunctioning thyroid adenoma
Non-medullary thyroid cancer 2
SRGAP1
Non-medullary thyroid cancer 3
Non-medullary thyroid cancer 4
Non-medullary thyroid cancer 4
Non-medullary thyroid cancer 5
Thyroid carcinoma with thyrotoxicosis

References:

1.

He H et al. (2013) SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility.

external link
2.

Vriens MR et al. (2009) Clinical features and genetic predisposition to hereditary nonmedullary thyroid cancer.

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3.

Bonora E et al. (2010) Genetic Predisposition to Familial Nonmedullary Thyroid Cancer: An Update of Molecular Findings and State-of-the-Art Studies.

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4.

OMIM.ORG article

Omim 188470 external link
Update: Aug. 14, 2020
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