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Familial cold autoinflammatory syndrome 3

Familial cold autoinflammatory syndrome 3 (FCAS3) is an autosomal dominant disorder caused by mutations of the PLCG2 gene. It is characterized by recurrent episodes of skin rash with arthralgias, myalgias, fever and chills. Typically those attacks occur after exposure to cold.

Systematic

Familial cold autoinflammatory syndromes
Familial cold autoinflammatory syndrome 1
Familial cold autoinflammatory syndrome 2
Familial cold autoinflammatory syndrome 3
PLCG2
Familial cold autoinflammatory syndrome 4

References:

1.

Ombrello MJ et. al. (2012) Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions.

external link
2.

Gandhi C et. al. (2009) Familial atypical cold urticaria: description of a new hereditary disease.

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Update: Aug. 14, 2020
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