Autoimmune diabetes 19 is a diabetes mellitus type 1 that are pathogentically linked to genetic variants in a locus that is not exactly determined yet. It is on chromosome 2q24.3 and stretches about 10 megabases. Many genes are in that region.
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Smyth DJ et al. (2006) A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. |
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Liu S et al. (2009) IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells. |
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Nejentsev S et al. (2009) Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes. |