Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Gastric cancer

In some Gastric cancers somatic mutations of the CASP10 gene can be found.

Systematic

Hereditary tumors
Capillary infantile hemangioma
Carcinoid tumor of lung
Gastric cancer
CASP10
Hereditary brain tumors
Hereditary malign blood disorders
Hereditary renal tumors
Lymphangiomyomatosis
Multiple self-healing palmoplantar carcinoma
Neurofibromatosis
Susceptibility to Kaposi sarcoma
lipoma

References:

1.

González CA et al. (2002) Genetic susceptibility and gastric cancer risk.

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2.

Lynch HT et al. (1996) Hereditary nonpolyposis colorectal cancer (Lynch syndrome). An updated review.

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3.

Renault B et al. (1996) Microsatellite instability and mutations of p53 and TGF-beta RII genes in gastric cancer.

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4.

Keller G et al. (1996) Analysis for microsatellite instability and mutations of the DNA mismatch repair gene hMLH1 in familial gastric cancer.

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5.

Ottini L et al. (1997) Microsatellite instability in gastric cancer is associated with tumor location and family history in a high-risk population from Tuscany.

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6.

Nozawa H et al. (1998) Functionally inactivating point mutation in the tumor-suppressor IRF-1 gene identified in human gastric cancer.

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7.

Bevan S et al. (1999) Genetic predisposition to gastric cancer.

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8.

Palli D et al. (2001) Red meat, family history, and increased risk of gastric cancer with microsatellite instability.

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9.

Hemminki K et al. (2002) Familial and second gastric carcinomas: a nationwide epidemiologic study from Sweden.

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10.

Watson P et al. (1993) Extracolonic cancer in hereditary nonpolyposis colorectal cancer.

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11.

Kim CJ et al. (2004) Genetic alterations of the MYH gene in gastric cancer.

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12.

Houghton J et al. (2004) Gastric cancer originating from bone marrow-derived cells.

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13.

Aoki M et al. (2005) A full genome scan for gastric cancer.

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14.

Cho YG et al. (2005) Genetic alterations of the KLF6 gene in gastric cancer.

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15.

Chien J et al. (2006) Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity.

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16.

Canedo P et al. (2007) After Helicobacter pylori, genetic susceptibility to gastric carcinoma revisited.

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17.

et al. (2008) Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer.

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18.

Kwon JA et al. (2010) Short rare MUC6 minisatellites-5 alleles influence susceptibility to gastric carcinoma by regulating gene.

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19.

La Vecchia C et al. (1992) Family history and the risk of stomach and colorectal cancer.

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20.

Berman DM et al. (2003) Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.

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21.

Park WS et al. (2002) Inactivating mutations of the caspase-10 gene in gastric cancer.

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22.

None (1988) A human model of gastric carcinogenesis.

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23.

Kakiuchi H et al. () Familial gastric cancer in the Japanese population is frequently located at the cardiac region.

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24.

Caldas C et al. (1999) Familial gastric cancer: overview and guidelines for management.

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25.

Huntsman DG et al. (2001) Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations.

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26.

None (1965) THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO-CALLED INTESTINAL-TYPE CARCINOMA. AN ATTEMPT AT A HISTO-CLINICAL CLASSIFICATION.

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27.

Horii A et al. (1992) The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer.

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28.

El-Omar EM et al. (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer.

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29.

Scott N et al. (1990) Helicobacter gastritis and intestinal metaplasia in a gastric cancer family.

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30.

Zanghieri G et al. (1990) Familial occurrence of gastric cancer in the 2-year experience of a population-based registry.

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31.

Motomura K et al. (1988) Loss of alleles at loci on chromosome 13 in human primary gastric cancers.

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32.

Howson CP et al. (1986) The decline in gastric cancer: epidemiology of an unplanned triumph.

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33.

Thomsen M et al. (1981) Association of pernicious anemia and intrinsic factor antibody with HLA-D.

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34.

Hsieh LL et al. (1995) Loss of heterozygosity of APC/MCC gene in differentiated and undifferentiated gastric carcinomas in Taiwan.

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35.

Kim CJ et al. (1995) Detection of 17p loss in gastric carcinoma using polymerase chain reaction.

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36.

Goldgar DE et al. (1994) Systematic population-based assessment of cancer risk in first-degree relatives of cancer probands.

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