Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Psoriasis susceptibility 11

Psoriasis is quite heritable. It is associated with various loci throughout the genome. The type 11 susceptibility is associates with 5q31.1-q33.1 .

Systematic

Psoriasis
CARD14 associated psoriasis
Psoriasis 14
Psoriasis 15
Psoriasis susceptibility 1
Psoriasis susceptibility 10
Psoriasis susceptibility 11
Psoriasis susceptibility 12
Psoriasis susceptibility 13
Psoriasis susceptibility 3
Psoriasis susceptibility 4
Psoriasis susceptibility 5
Psoriasis susceptibility 6
Psoriasis susceptibility 7
Psoriasis susceptibility 8
Psoriasis susceptibility 9

References:

1.

Zhang XJ et al. (2009) Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21.

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2.

Kauffman CL et al. (2004) A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis.

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3.

Cargill M et al. (2007) A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes.

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4.

Capon F et al. (2007) Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

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5.

Hüffmeier U et al. (2009) Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis.

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6.

Nair RP et al. (2009) Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.

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7.

Tsunemi Y et al. (2002) Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris.

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Update: Aug. 14, 2020
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