Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Genetic susceptibility to aspergillosis

Susceptibility to aspergillus infection may be genetically determined by mutations of the CLEC1A und CLEC7A genes.


Hereditary susceptibility to infections
Disorders of mRNA editing
Familial candidiasis
Genetic susceptibility to aspergillosis
HIV resistance
IRAK4 deficiency
Invasive pneumococcal disease
Measles infection susceptibility
Meningococcal infection susceptibility
Resistance to trypanosoma brucei
Septic shock
Susceptibility to bacteremia 1
Susceptibility to malaria
Susceptibility to mycobacterial diseases
Susceptibility to pseudomonas infection
X-linked mendelian susceptibility to mycobacterial diseases due to IKBKG deficiency



Yokota K et al. (2001) Identification of a human homologue of the dendritic cell-associated C-type lectin-1, dectin-1.

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Cunha C et al. (2010) Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity.

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Stappers MHT et al. (2018) Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus.

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Seo KW et al. (2005) Protective role of interleukin-10 promoter gene polymorphism in the pathogenesis of invasive pulmonary aspergillosis after allogeneic stem cell transplantation.

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Carvalho A et al. (2008) Polymorphisms in toll-like receptor genes and susceptibility to pulmonary aspergillosis.

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Bochud PY et al. (2008) Toll-like receptor 4 polymorphisms and aspergillosis in stem-cell transplantation.

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None (2008) TLR polymorphisms and the risk of invasive fungal infections.

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Levitz SM et al. (2009) Toll-like receptor 4 polymorphisms and aspergillosis.

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Cervera C et al. (2009) Toll-like receptor 4 polymorphisms and aspergillosis.

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Asakura Y et al. (2009) Toll-like receptor 4 polymorphisms and aspergillosis.

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Update: Aug. 14, 2020
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