Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Aldose reductase

This gene is intensly researched into its contribution to diabetic complications. Several genetic variations have been associated with diabetic nephropathy.

Genetests:

Research Method Carrier testing
Turnaround 5 days
Specimen type genomic DNA
Clinic Method Massive parallel sequencing
Turnaround 25 days
Specimen type genomic DNA

Related Diseases:

Diabetic nephropathy
ACE
AGT
AKR1B1

References:

1.

Wolford JK et al. (2006) Variants in the gene encoding aldose reductase (AKR1B1) and diabetic nephropathy in American Indians.

external link
2.

Graham A et al. (1991) Structure of the human aldose reductase gene.

external link
3.

Shah VO et al. (1997) Aldose reductase gene expression is increased in diabetic nephropathy.

external link
4.

NCBI article

NCBI 231 external link
5.

OMIM.ORG article

Omim 103880 external link
6.

Wikipedia article

Wikipedia EN (Aldose_reductase) external link
Update: Aug. 14, 2020
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