Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Aldose reductase

This gene is intensly researched into its contribution to diabetic complications. Several genetic variations have been associated with diabetic nephropathy.

Genetests:

Research Method Carrier testing
Turnaround 5 days
Specimen type genomic DNA
Clinic Method Massive parallel sequencing
Turnaround 25 days
Specimen type genomic DNA

Related Diseases:

Diabetic nephropathy
ACE
AGT
AKR1B1

References:

1.

Wolford JK et al. (2006) Variants in the gene encoding aldose reductase (AKR1B1) and diabetic nephropathy in American Indians.

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2.

Graham A et al. (1991) Structure of the human aldose reductase gene.

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3.

Shah VO et al. (1997) Aldose reductase gene expression is increased in diabetic nephropathy.

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4.

NCBI article

NCBI 231 [^]
5.

OMIM.ORG article

Omim 103880 [^]
6.

Wikipedia article

Wikipedia EN (Aldose_reductase) [^]
Update: April 29, 2019