Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Sodium-glucose transporter 2

The transporter manages tubular glucose reabsorption. If this function is impaired the renal glucose threshold is decreased and glucosuria results even if the plasma glucose level is normal.

Genetests:

Clinic Method Carrier testing
Turnaround 5 days
Specimen type genomic DNA
Clinic Method Massive parallel sequencing
Turnaround 25 days
Specimen type genomic DNA
Clinic Method Genomic sequencing of the entire coding region
Turnaround 20 days
Specimen type genomic DNA

Related Diseases:

Renal Glucosuria
SLC5A2

References:

1.

None (2001) Renal Na(+)-glucose cotransporters.

external link
2.

Calado J et al. (2006) Familial renal glucosuria: SLC5A2 mutation analysis and evidence of salt-wasting.

external link
3.

NCBI article

NCBI 6524 external link
4.

OMIM.ORG article

Omim 182381 external link
5.

Orphanet article

Orphanet ID 119697 external link
6.

Wikipedia article

Wikipedia EN (SGLT2) external link
Update: Aug. 14, 2020
Copyright © 2005-2020 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD
Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944
Sitemap | Webmail | Disclaimer | Privacy Issues