Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Epidermal growth factor

Epidermal growth factor is a membrane bound hormone that regulates magnesium excretion in the distal convoluted tubule. A mutation might cause autosomal recessive renal hypomagnesemia 4.

Genetests:

Clinic Method Carrier testing
Turnaround 5 days
Specimen type genomic DNA
Clinic Method Genomic sequencing of the entire coding region
Turnaround 25 days
Specimen type genomic DNA
Clinic Method Massive parallel sequencing
Turnaround 25 days
Specimen type genomic DNA

Related Diseases:

Hypomagnesemia with normocalciuria
EGF

References:

1.

Groenestege WM et al. (2007) Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.

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Update: Sept. 26, 2018