Cytochrome P450, family 4, subfamily F, polypeptide 2
This gene encodes a member of the cytochrome P450 superfamily of enzymes. It is involved in drug metabolism, in particular coumarin derivates.
Kikuta Y et al. (1999) Expression and molecular cloning of human liver leukotriene B4 omega-hydroxylase (CYP4F2) gene.
Stec DE et al. (2007) Functional polymorphism in human CYP4F2 decreases 20-HETE production.
Caldwell MD et al. (2008) CYP4F2 genetic variant alters required warfarin dose.
Update: Sept. 26, 2018