Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The CYP4F2 gene encodes a member of the cytochrome P450 superfamily of enzymes. It is involved in drug metabolism, in particular coumarin derivates.
| Clinic | Method | Massive parallel sequencing |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Research | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
Disturbances of cytochrome p450 system
|
||||
|
CYP1A2
|
|||
|
|
CYP2A6
|
|||
|
|
CYP2C9
|
|||
|
|
CYP2D6
|
|||
|
|
CYP3A4
|
|||
|
|
CYP4F2
|
|||
|
Siponimod intolerance
|
|||
|
|
|
CYP2C9
|
||
|
|
|
|
|
| 1. |
Caldwell MD et al. (2008) CYP4F2 genetic variant alters required warfarin dose. 
|
| 2. |
Kikuta Y et al. (1999) Expression and molecular cloning of human liver leukotriene B4 omega-hydroxylase (CYP4F2) gene.
|
| 3. |
Stec DE et al. (2007) Functional polymorphism in human CYP4F2 decreases 20-HETE production.
|
| 4. |
Orphanet article Orphanet ID 286575
|
| 5. |
NCBI article NCBI 8529
|
| 6. |
OMIM.ORG article Omim 604426
|
| 7. |
Wikipedia article Wikipedia EN (CYP4F2)
|
 |
Copyright © 2005-2021 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944 Sitemap | Webmail | Disclaimer | Privacy Issues |