Glypican 5
The GPC5 gene encodes a cell surface protein forming heparan sulfate proteoglycans and being probably involved in cell division and growth regulation. Variations seem to be associated with nephrotic syndrome.
Genetests:
Related Diseases:
References:
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Neat MJ et al. (2001) Localisation of a novel region of recurrent amplification in follicular lymphoma to an approximately 6.8 Mb region of 13q32-33.
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2. |
Mao X et al. (2002) Comparative genomic hybridization analysis of primary cutaneous B-cell lymphomas: identification of common genomic alterations in disease pathogenesis.
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3. |
Yu W et al. (2003) GPC5 is a possible target for the 13q31-q32 amplification detected in lymphoma cell lines.
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4. |
Okamoto K et al. (2011) Common variation in GPC5 is associated with acquired nephrotic syndrome.
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5. |
Veugelers M et al. (1997) Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family.
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6. |
Knuutila S et al. (1998) DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.
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7. |
NCBI article
NCBI 2262
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8. |
OMIM.ORG article
Omim 602446
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9. |
Wikipedia article
Wikipedia EN (Glypican_5)
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Update: Aug. 14, 2020