Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
The COL4A3BP gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. How this kinase is involved in the pathogenesis of Goodpasture syndrome remains to be clarified.
Raya A et al. (1999) Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen.
Hanada K et al. (2003) Molecular machinery for non-vesicular trafficking of ceramide.
Update: Sept. 26, 2018