Apolipoprotein M
APOM encodes apolipoprotein M, a protein that plays a role in lipoprotein metabolism and immune modulation.
Expression
Apolipoprotein M is secreted by endothelial cells ans mostly remains membrane bound. It is also be found in HDL and to a lesser degree LDL and triglyceride-rich lipoproteins. PLasma concentration is 0.9µmol/l. 95% is bound to HDL.
Genetests:
Research |
Method |
Carrier testing |
Turnaround |
5 days |
Specimen type |
genomic DNA |
Related Diseases:
References:
1. |
Xu N et al. (1999) A novel human apolipoprotein (apoM).
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2. |
Wolfrum C et al. (2005) Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis.
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3. |
Albertella MR et al. (1996) Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B).
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4. |
NCBI article
NCBI 55937
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5. |
OMIM.ORG article
Omim 606907
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6. |
Wikipedia article
Wikipedia EN (APOM)
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Update: Aug. 14, 2020