APOM encodes apolipoprotein M, a protein that plays a role in lipoprotein metabolism and immune modulation.
Apolipoprotein M is secreted by endothelial cells ans mostly remains membrane bound. It is also be found in HDL and to a lesser degree LDL and triglyceride-rich lipoproteins. PLasma concentration is 0.9µmol/l. 95% is bound to HDL.
Xu N et al. (1999) A novel human apolipoprotein (apoM).
Wolfrum C et al. (2005) Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis.
Albertella MR et al. (1996) Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B).
NCBI 55937 [^]
Omim 606907 [^]
Wikipedia EN (APOM) [^]
Update: April 29, 2019