The TREH gene encodes an enzyme that cleaves trehalose, a disaccharide formed in fungi. Mutations cause autosomal dominant trehalase deficiency that is characterized by gastrointestinal symptoms after the ingestion of young mushrooms.
Oesterreicher TJ et al. (2001) Cloning, characterization and mapping of the mouse trehalase (Treh) gene.
Ruf J et al. (1990) Rabbit small intestinal trehalase. Purification, cDNA cloning, expression, and verification of glycosylphosphatidylinositol anchoring.
Sasai-Takedatsu M et al. (1996) Human trehalase: characterization, localization, and its increase in urine by renal proximal tubular damage.
Ishihara R et al. (1997) Molecular cloning, sequencing and expression of cDNA encoding human trehalase.
Orphanet ID 158077
Wikipedia EN (Trehalase)
Update: Aug. 14, 2020