Neutral alpha-glucosidase AB
The GANAB gene encodes an enzyme that play a role in maturation and surface localization of cilia. Mutations cause autosomal dominant polycystic liver and kidney disease.
Porath B et. al. (2016) Mutations in GANAB, Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease.
Martiniuk F et. al. (1983) Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11.
Trombetta ES et. al. (1996) Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit.
Update: Sept. 26, 2018