Solute carrier organic anion transporter family member 1B3
The SLCO1B3 gene encodes an anion transporter expressed in liver cells where it is responsible for the uptake of solutes. Mutations are associated with digenic Rotor type hyperbilirubinemia together with mutations in gene SLCO1B1.
van de Steeg E et al. (2012) Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.
König J et al. (2000) Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide.
Mikkaichi T et al. (2004) Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.
Orphanet ID 292437
Wikipedia EN (SLCO1B3)
Update: Aug. 14, 2020