Cyclic AMP-responsive element-binding protein 3-like protein 3
The CREB3L3 gene encodes a transcription factor which is involvee in the regulation of fatty acid oxidation. In animal modes mutations of that gene cause hyperlipidemia.
Cefalù AB et. al. () Identification of a novel LMF1 nonsense mutation responsible for severe hypertriglyceridemia by targeted next-generation sequencing.
Omori Y et. al. (2001) CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expression.
Zhang K et. al. (2006) Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response.
Nakagawa Y et. al. (2016) CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.
Update: Sept. 26, 2018