The KLB gene encodes a cDNA quite similar to klotho. Therefore a similar function or interaction can be hypothesized.
Ito S et. al. (2000) Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein.
Ito S et. al. (2005) Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho.
Ogawa Y et. al. (2007) BetaKlotho is required for metabolic activity of fibroblast growth factor 21.
Update: Sept. 26, 2018