The APOBEC2 gene encodes a protein of the APOBEC family. Enzymes of this family are responsible for mRNA editing. They introduce base exchanges before the protein is translated, which plays an important role in defense of viral infections and lipid metabolism.
Liao W et. al. (1999) APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family.
Prochnow C et. al. (2007) The APOBEC-2 crystal structure and functional implications for the deaminase AID.
Sato Y et. al. (2010) Deficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy.
Update: Sept. 26, 2018