Homeobox protein SIX2
The SIX2 gene encodes a transcription factor that is involved in development of the renal and hearing systems.
Genetests:
Related Diseases:
References:
1. |
Oliver G et al. (1995) Homeobox genes and connective tissue patterning.
|
2. |
Boucher CA et al. (2000) Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2.
|
3. |
Mao Z et al. (2017) TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro.
|
4. |
Chung E et al. (2016) Notch signaling promotes nephrogenesis by downregulating Six2.
|
5. |
Liu J et al. (2016) Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis.
|
6. |
Guan J et al. (2016) SIX2 haploinsufficiency causes conductive hearing loss with ptosis in humans.
|
7. |
None () Correction: Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney.
|
8. |
NCBI article
NCBI 10736
|
9. |
OMIM.ORG article
Omim 604994
|
10. |
Orphanet article
Orphanet ID 496461
|
11. |
Wikipedia article
Wikipedia EN (SIX2)
|
Update: Aug. 14, 2020