The SIX2 gene encodes a transcription factor that is involved in development of the renal and hearing systems.
Clinic | Method | Carrier testing |
Turnaround | 5 days | |
Specimen type | genomic DNA |
Clinic | Method | Massive parallel sequencing |
Turnaround | 25 days | |
Specimen type | genomic DNA |
Research | Method | Genomic sequencing of the entire coding region |
Turnaround | 25 days | |
Specimen type | genomic DNA |
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1. |
Oliver G et al. (1995) Homeobox genes and connective tissue patterning. ![]() |
2. |
Boucher CA et al. (2000) Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2. ![]() |
3. |
Mao Z et al. (2017) TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro. ![]() |
4. |
Chung E et al. (2016) Notch signaling promotes nephrogenesis by downregulating Six2. ![]() |
5. |
Liu J et al. (2016) Six2 Is a Coordinator of LiCl-Induced Cell Proliferation and Apoptosis. ![]() |
6. |
Guan J et al. (2016) SIX2 haploinsufficiency causes conductive hearing loss with ptosis in humans. ![]() |
7. |
None () Correction: Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney. ![]() |
8. |
NCBI article NCBI 10736![]() |
9. |
OMIM.ORG article Omim 604994![]() |
10. |
Orphanet article Orphanet ID 496461![]() |
11. |
Wikipedia article Wikipedia EN (SIX2)![]() |