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Eosinophil peroxidase

The EPX gene encodes a peroxidase wich is predominantly expressed in eosinophils. An association with allergic food reactions is discussed.

Genetests:

Clinic Method Carrier testing
Turnaround 5 days
Specimen type genomic DNA
Clinic Method Massive parallel sequencing
Turnaround 25 days
Specimen type genomic DNA
Research Method Genomic sequencing of the entire coding region
Turnaround 25 days
Specimen type genomic DNA

Related Diseases:

Eosinophil peroxidase deficiency
EPX

References:

1.

Romano M et al. (1994) Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect.

external link
2.

Nakagawa T et al. (2001) Eosinophilic peroxidase deficiency: Identification of a point mutation (D648N) and prediction of structural changes.

external link
3.

Sakamaki K et al. (1989) Molecular cloning and characterization of a chromosomal gene for human eosinophil peroxidase.

external link
4.

Sakamaki K et al. (2000) The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17.

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5.

NCBI article

NCBI 8288 external link
6.

OMIM.ORG article

Omim 131399 external link
7.

Wikipedia article

Wikipedia EN (Eosinophil_peroxidase) external link
Update: Aug. 14, 2020
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