Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The SRGAP1-gene encodes a protein that functions as a GTPase activator ind is thereby involved in signal tranduction. Mutations cause autosomal dominant non-medullary thyroid cancer 2.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Research | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| 1. |
Nagase T et al. (2000) Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. 
|
| 2. |
He H et al. (2013) SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility.
|
| 3. |
Wong K et al. (2001) Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
|
| 4. |
NCBI article NCBI 57522
|
| 5. |
OMIM.ORG article Omim 606523
|
| 6. |
Wikipedia article Wikipedia EN (SRGAP1)
|
 |
Copyright © 2005-2024 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944 Sitemap | Webmail | Disclaimer | Privacy Issues | Website Credits |
