Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Thyrotropin releasing hormone (TRH)

The TRH gene encodes thyrotropin releasing hormone, mutations of which cause hypothalamic hypothyreosis.

Genetests:

Clinic Method Carrier testing
Turnaround 5 days
Specimen type genomic DNA
Research Method Genomic sequencing of the entire coding region
Turnaround 25 days
Specimen type genomic DNA

Related Diseases:

Thyrotropin-releasing hormone deficiency
TRH

References:

1.

Krashes MJ et. al. (2014) An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger.

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2.

Yamada M et. al. (1991) Assignment of human preprothyrotropin-releasing hormone (TRH) gene to chromosome 3.

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3.

Yamada M et. al. (1990) Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro thyrotropin-releasing hormone.

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4.

Roller ML et. al. (1995) Localization of the thyrotropin-releasing hormone gene, Trh, on mouse chromosome 6.

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5.

Yamada M et. al. (1999) Assignment of the thyrotropin-releasing hormone gene (TRH) to human chromosome 3q13.3-->q21 by in situ hybridization.

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6.

Gáspár E et. al. (2010) Thyrotropin releasing hormone (TRH): a new player in human hair-growth control.

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Update: Sept. 26, 2018