Mitogen-activated protein kinase-binding protein 1
The MAPKBP1 gene encodes a scaffold protein that is involved in signal transduction. Mutations cause autosomal recessive nephronophthisis type 20.
Macia MS et al. (2017) Mutations in MAPKBP1 Cause Juvenile or Late-Onset Cilia-Independent Nephronophthisis.
Koyano S et al. (1999) A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.
Cohen-Katsenelson K et al. (2013) Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins.
Update: Aug. 14, 2020