Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders


Inflammation is the immunological reaction that triggers a specific response in tissues that have access to the vascular system. The classical signs of inflammation; rubor (redness), calor (heat), dolor (pain), tumor (swelling), and functio laesa (loss of function); are present only if the inflammation occurs near skin surface. If internal organs are affected inflammation is rather defined histological as infiltration, exudate, and fibrosis.


Familial cold autoinflammatory syndrome 1
In Familial cold autoinflammatory syndrome 1 inflammation develops after exposure to cold.
Familial mediterranean fever
Inflammation is predominantly a recurring serositis.
TNF receptor-associated periodic syndrome
Typical of periodic fever are recurrent inflammatory attacks and usually an instructive family history. Serositis may develop but not amyloidosis.
Muckle-Wells syndrome
In Muckle-Wells syndrome inflammation is dominated by episodic skin rash and arthralgias.
Update: April 29, 2019