Inflammation is the immunological reaction that triggers a specific response in tissues that have access to the vascular system. The classical signs of inflammation; rubor (redness), calor (heat), dolor (pain), tumor (swelling), and functio laesa (loss of function); are present only if the inflammation occurs near skin surface. If internal organs are affected inflammation is rather defined histological as infiltration, exudate, and fibrosis.
Familial cold autoinflammatory syndrome 1 | |
In Familial cold autoinflammatory syndrome 1 inflammation develops after exposure to cold. |
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Familial Mediterranean fever | |
Inflammation is predominantly a recurring serositis. |
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TNF receptor-associated periodic syndrome | |
Typical of periodic fever are recurrent inflammatory attacks and usually an instructive family history. Serositis may develop but not amyloidosis. |
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Muckle-Wells syndrome | |
In Muckle-Wells syndrome inflammation is dominated by episodic skin rash and arthralgias. |