Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
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Calcinosis is the calcification (calcium deposition) in soft tissues that is outside the bones.


Calcinosis can be caused by local or systemic factors. The former are injuries or injections; the latter hyperparathyroidism or disorders of calcium and phosphate metabolism.


Several forms of Calcinosis can can be clinically distinguished:

  • c. circumscripta
  • c. cutis
  • c. intervertebralis calcification of nucleus pulposus (often) and anulus fibrosis (rare) of one or many intervertebral disks.
  • tumoral c. sometimes large soft tissue calcifications around big joints like shoulder, elbow, and hip. Symptoms are mainly caused by nerve compression.
  • c. universalis
  • c. metastatica
  • c. interstitialis


Hyperphosphatemic familial tumoral calcinosis
Calcinosis tumoralis is caused by prolonged hyperphosphatemia.
Update: Aug. 14, 2020
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