Acanthosis nigricans is a grayish brown hyperpigmentation of the skin in body folds such as neck, the armpits, groin, and navel.
Alström syndrome | |
In Alstrom syndrome besides of obesity and diabetes an acanthosis nigricans can be seen. |
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Crouzon syndrome | |
Among several other dysmorphic features acanthosis nigricans is typical of Crouzon syndrome, in particular when caused by FGFR3 mutations. |
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Diabetes mellitus with insulin resistance and acanthosis nigricans | |
All types of insulin resistance caused by mutations of the insulin receptor gene are accompanied by acanthosis nigricans. |
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Leprechaunism | |
Insulin resistance in leprechaunism is accompanied by acanthosis nigricans. |
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Lipodystrophy | |
Generalized and partial lipodystrophy may be accompanied by acanthosis nigricans. |
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Generalized lipodystrophy | |
Generalized lipodystrophy is accompanied by acanthosis nigricans. |
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Familial partial lipodystrophy type 2 | |
Partial lipodystrophy 2 is accompanied by acanthosis nigricans. |