Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Knudson's two-hit hypothesis of tumorigenesis

Knudson’s two-hit hypothesis of tumorigenesis claims that a germline mutation of a tumor suppressor gene is accompanied by an additional somatic mutation. Then the two alleles of a protective gene being silenced promotes tumorigenesis.

Copyright © 2005-2021 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD
Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944
Sitemap | Webmail | Disclaimer | Privacy Issues | Website Credits