Fibroblast growth factor receptor 4
The FGFR4 gene encodes an FGF receptor. Interaction of that receptor with tumor progression is assumed.
Genetests:
Research |
Method |
Carrier testing |
Turnaround |
5 days |
Specimen type |
genomic DNA |
Related Diseases:
References:
1. |
Keegan K et al. (1991) Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3.
|
2. |
Avraham KB et al. (1994) Mapping of murine fibroblast growth factor receptors refines regions of homology between mouse and human chromosomes.
|
3. |
Warrington JA et al. (1992) A radiation hybrid map of 18 growth factor, growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5.
|
4. |
Armstrong E et al. (1992) Localization of the fibroblast growth factor receptor-4 gene to chromosome region 5q33-qter.
|
5. |
Vainikka S et al. (1992) Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction.
|
6. |
Partanen J et al. (1991) FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.
|
7. |
Holtrich U et al. (1991) Two additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinase.
|
8. |
Kostrzewa M et al. (1998) Genomic structure and complete sequence of the human FGFR4 gene.
|
9. |
Jung J et al. (1999) Initiation of mammalian liver development from endoderm by fibroblast growth factors.
|
10. |
Bange J et al. (2002) Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele.
|
11. |
Taylor JG et al. (2009) Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.
|
12. |
NCBI article
NCBI 2264
|
13. |
OMIM.ORG article
Omim 134935
|
14. |
Wikipedia article
Wikipedia EN (Fibroblast_growth_factor_receptor_4)
|
Update: Aug. 14, 2020