Graves disease

None (1972) Genetics of Graves' disease.

MARTIN L et al. (1951) The hereditary and familial aspects of toxic nodular goitre (secondary thyrotoxicosis).

Simmonds MJ et al. (2005) Regression mapping of association between the human leukocyte antigen region and Graves disease.

Sutherland A et al. (2007) Genomic polymorphism at the interferon-induced helicase (IFIH1) locus contributes to Graves' disease susceptibility.

Brand OJ et al. (2009) Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.

None (1945) The hereditary and familial aspects of exophthalmic goitre and nodular goitre.

None (1990) Receptor autoimmunity in endocrine disorders.

Payami H et al. (1989) Relative predispositional effects (RPEs) of marker alleles with disease: HLA-DR alleles and Graves disease.

Wit JM et al. (1986) Thyroid-stimulating immunoglobulins and thyroid function tests in two siblings with neonatal thyrotoxicosis.

Horwitz DL et al. (1977) Graves' disease associated with familial deficiency of thyroxine-binding globulin.

Chu X et al. (2011) A genome-wide association study identifies two new risk loci for Graves' disease.

Uno H et al. (1981) Two major genes, linked to HLA and Gm, control susceptibility to Graves' disease.

Bahn RS et al. (1993) Pathogenesis of Graves' ophthalmopathy.

Shimojo N et al. (1996) Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule.

de Roux N et al. (1996) Analysis of the thyrotropin receptor as a candidate gene in familial Graves' disease.

Tomer Y et al. (1997) Mapping of a major susceptibility locus for Graves' disease (GD-1) to chromosome 14q31.

None (1976) Humoral and genetic factors in thyrotoxic Graves disease and neonatal thyrotoxicosis.

Barbesino G et al. (1998) Linkage analysis of candidate genes in autoimmune thyroid disease. II. Selected gender-related genes and the X-chromosome. International Consortium for the Genetics of Autoimmune Thyroid Disease.

Heward JM et al. (1998) Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: replication using a population case control and family-based study.

Robertson DM et al. (2003) Retinal microvascular abnormalities in patients treated with external radiation for graves ophthalmopathy.

Ueda H et al. (2003) Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.

Chen CR et al. (2003) The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim.

Hiratani H et al. (2005) Multiple SNPs in intron 7 of thyrotropin receptor are associated with Graves' disease.

Dechairo BM et al. (2005) Association of the TSHR gene with Graves' disease: the first disease specific locus.

Paschke R et al. (1997) The thyrotropin receptor in thyroid diseases.

Akamizu T et al. (2003) Association study of autoimmune thyroid disease at 5q23-q33 in Japanese patients.

Barbero P et al. (2004) Choanal atresia associated with prenatal methimazole exposure: three new patients.

Ban Y et al. (2000) Vitamin D receptor gene polymorphism is associated with Graves' disease in the Japanese population.

Donner H et al. (1997) CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus.

Vaidya B et al. (1999) The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus.

Chen QY et al. (1999) HLA-DRB1*08, DRB1*03/DRB3*0101, and DRB3*0202 are susceptibility genes for Graves' disease in North American Caucasians, whereas DRB1*07 is protective.

Farid NR et al. (1979) A study of human leukocyte D locus related antigens in Graves' disease.

Pearce SH et al. (1999) Further evidence for a susceptibility locus on chromosome 20q13.11 in families with dominant transmission of Graves disease.

Chen QY et al. (2000) The human leukocyte antigen HLA DRB3*020/DQA1*0501 haplotype is associated with Graves' disease in African Americans.

Marcocci C et al. (2001) Comparison of the effectiveness and tolerability of intravenous or oral glucocorticoids associated with orbital radiotherapy in the management of severe Graves' ophthalmopathy: results of a prospective, single-blind, randomized study.

Hermenegildo C et al. (2002) Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in hyperthyroid patients.

Hadj Kacem H et al. (2003) PDS is a new susceptibility gene to autoimmune thyroid diseases: association and linkage study.

Kretowski A et al. (2003) Intercellular adhesion molecule 1 gene polymorphisms in Graves' disease.

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