Crigler-Najjar syndrome 2 is an autosomal recessive disorder caused by mutations of the UGT1A1-Gene. Because of some residual enzyme function the clinical presentation is milder than in type 1.
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Petit F et al. (2006) Crigler-Najjar type II syndrome may result from several types and combinations of mutations in the UGT1A1 gene.
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OMIM.ORG article Omim 606785
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