Complement component C1s deficiency

Complement component C1s deficiency is an autosomal recessive disorder caused by mutations of the C1S gene. Clinical presentation include autimmune disorderss such as lupus erythematodes and glomerulonephrtis.

Systematic

Early pathway complement deficiencies
	Complement component C1q deficiency
	Complement component C1r/C1s deficiency
	Complement component C1s deficiency
		C1S

References:

1.	Inoue N et al. (1998) Selective complement C1s deficiency caused by homozygous four-base deletion in the C1s gene.

2.	Dragon-Durey MA et al. (2001) Molecular basis of a selective C1s deficiency associated with early onset multiple autoimmune diseases.

3.	OMIM.ORG article Omim 613783