Combined pituitary hormone deficiency is a group of disorders of developmental defects of the pituitary gland. The cause is in mutations of pituitary specific transcription factors. Clinical signs are dominated by the hormone deficiencies, but also defects in the central nervous system can be observed. Inheritance is dominant or recessive.
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OMIM.ORG article Omim 613038 |
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Orphanet article Orphanet ID 231720 |
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Wikipedia article Wikipedia EN (Hypopituitarism) |